Experimental Data

Skin Absorption Test

lab-data-02

Experimental data show that the amount of spicule remaining on the surface of the skin decreased by an average of more than 60% after 24 hours, less than 2% of spicule remained after 120 hours, and was completely eliminated after 240 hours.

lab-data-01

Experimental data show that less than 15% of spicule remains after one wash, and that spicule is almost completely removed after 4-5 washes

the-macromolecule-penetration

Spicule Transportation Active Ingredient

  • SHS combined with catlonic fexibie liposome can overcome the first barrierof siRNA delivery-stratum corneum
  • The combined use of SHS and CFL(0.05%), significantiy enhanced the skin penetration and deposition of siRNA into deep skin layers.
  • CFL(0.05%) can overcome the second barrier of siRNA delivery-skin cell membrane
  • CFL(0,05%) as a siRNA carrier system resulted in a significant decrease in the expression of GAPDH protein in the cells.